TPS-EDIT<\/p>\n<\/div>
The zebrafish (Danio rerio)<\/em> has become a relevant vertebrate model for studying gene function.<\/h2><\/span><\/div><\/div><\/div><\/div><\/div>We estimate that 82% of the genes involved in human diseases have an ortholog in zebrafish, making it a relevant species model for studying the molecular and cellular consequences of genetic modification.<\/p>\n
TPS-EDIT has expertise in a range of genome-editing techniques,<\/strong> including gene knockout (KO), gene modification or insertion of fluorescent reporters (KI), CRISPANTS and Prime Editing. Thanks to its collaboration with the TACGENE<\/u><\/a> platform, TPS-EDIT uses the latest genome-editing technologies to offer the technical solutions best suited to your project.<\/p>\nTPS-EDIT has a modern (2020) and spacious animal facility<\/strong> handled by TPS-AQUA<\/u><\/a><\/span>, which is essential to the success of the projects that our users entrust to us. Once lines have been produced, we can offer customised phenotypic characterisation using the expertise of\u00a0TPS-PHENO<\/u><\/a><\/span> and TPS-INFO<\/u><\/a><\/span>.<\/p>\n<\/div><\/div><\/div><\/div><\/div>![](\"https:\/\/tefor.net\/wp-content\/uploads\/VIGNETTE_TPS-EDIT.jpg\" "\\"VIGNETTE_TPS-EDIT\\"")
<\/span><\/div><\/div><\/div><\/i>Services<\/h4><\/a><\/li><\/i>R&D<\/h4><\/a><\/li><\/i>TRAININGS<\/h4><\/a><\/li><\/i>NETWORKS<\/h4><\/a><\/li><\/ul><\/div><\/i>Services<\/h4><\/a><\/li><\/ul><\/div>\n\n- The TPS-EDIT <\/strong>\u00a0lines<\/u><\/a><\/span> genetically edited by the CRISPR-Cas9 system, selecting the most innovative techniques.<\/li>\n<\/ul>\nOUR CATALOG<\/span><\/a><\/div><\/div>
<\/i>R&D<\/h4><\/a><\/li><\/ul><\/div>\nTechnological development of the TPS-EDIT<\/strong> team focuses on:<\/p>\n\n- refining genomic modifications: faithful reproduction of point mutations<\/li>\n
- increasing the efficiency of KO and KI by CRISPR (reducing the rate of mosaicism in F0)<\/li>\n
- developing genome editing by CRISPR\/Cas9 in Xenopus.<\/li>\n<\/ul>\nCONTACT US<\/span><\/a><\/div>\n<\/div>
<\/i>TRAININGS<\/h4><\/a><\/li><\/ul><\/div>\nTPS-EDIT<\/strong> regularly welcomes students (Bachelor or Master degrees, professional apprentices)<\/p>\nMORE INFORMATIONS<\/span><\/a><\/div>\n<\/div>
We estimate that 82% of the genes involved in human diseases have an ortholog in zebrafish, making it a relevant species model for studying the molecular and cellular consequences of genetic modification.<\/p>\n
TPS-EDIT has expertise in a range of genome-editing techniques,<\/strong> including gene knockout (KO), gene modification or insertion of fluorescent reporters (KI), CRISPANTS and Prime Editing. Thanks to its collaboration with the TACGENE<\/u><\/a> platform, TPS-EDIT uses the latest genome-editing technologies to offer the technical solutions best suited to your project.<\/p>\n TPS-EDIT has a modern (2020) and spacious animal facility<\/strong> handled by TPS-AQUA<\/u><\/a><\/span>, which is essential to the success of the projects that our users entrust to us. Once lines have been produced, we can offer customised phenotypic characterisation using the expertise of\u00a0TPS-PHENO<\/u><\/a><\/span> and TPS-INFO<\/u><\/a><\/span>.<\/p>\n<\/div><\/div><\/div><\/div><\/div> Technological development of the TPS-EDIT<\/strong> team focuses on:<\/p>\n TPS-EDIT<\/strong> regularly welcomes students (Bachelor or Master degrees, professional apprentices)<\/p>\n<\/span><\/div><\/div><\/div><\/i>Services<\/h4><\/a><\/li>
<\/i>R&D<\/h4><\/a><\/li>
<\/i>TRAININGS<\/h4><\/a><\/li>
<\/i>NETWORKS<\/h4><\/a><\/li><\/ul><\/div>
<\/i>Services<\/h4><\/a><\/li><\/ul><\/div>
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<\/i>R&D<\/h4><\/a><\/li><\/ul><\/div>
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<\/i>TRAININGS<\/h4><\/a><\/li><\/ul><\/div>
![\"CELPHEDIA](\"https:\/\/tefor.net\/wp-content\/uploads\/Celphedia_2025.jpg\")
<\/a><\/div><\/div><\/div>![\"IBISA](\"https:\/\/tefor.net\/wp-content\/uploads\/PARTENAIRES-ibiza-avenir.jpg\")
<\/a><\/div><\/div><\/div>![\"Universit\u00e9](\"https:\/\/tefor.net\/wp-content\/uploads\/paris-saclay_CNRS2025.jpg\")
<\/a><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/div>\n<\/p>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":7193,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"100-width.php","meta":{"footnotes":""},"class_list":["post-7128","page","type-page","status-publish","hentry"],"yoast_head":"\n